← Back to Cognitive Deep Dive

Dihexa

Angiotensin IV analogue — potent cognitive enhancer

Protocol Summary

Route
Oral / SubQ
Dose Range
5–20 mg oral, 1–5 mg subq
Cycling
Emerging — no established protocol
Evidence Tier
animal

Primary Benefits

Safety Profile

CAUTION: Pro-cancer concern via HGF/c-Met pathway. No human safety data. Research chemical only.

Research Findings

from peptide_kb — updated weekly

clinical-anecdotal clinical-anecdotal (1)

Peptides vs Supplements for Cognitive Enhancement — Dihexa, P21, Semax, Selank
youtube 2026-06-07 source →
Supplement formulator compares neuropeptides to traditional nootropics. Dihexa described as 'hundreds of times more powerful than lion's mane' for neurogenesis. P21+Dihexa combined in 'Neurorigen' product. Semax compared to alpha-GPC but far more potent. All peptides positioned as tools to combat neurodegenerative disease beyond what supplements alone can achieve. Also discusses dopamine resensitization via Semax, P21, Dihexa.