Ghrelin Activates Orexigenic NPY Neurons in the Arcuate Nucleus
Ghrelin, the hunger peptide hormone, exerts its appetite-stimulating effects by activating orexigenic neuropeptide Y (NPY) neurons located in the arcuate nucleus of the hypothalamus. This represents the mechanistic pathway through which ghrelin drives hunger signaling centrally. No dosages, study citations, or specific evidence sources are provided in the transcript.