PT-141 and Melanotan insufficient for finasteride-induced sexual dysfunction
Dr. Bachmeyer warns that men who develop post-finasteride syndrome (PFS) — permanent impotence in 35% of PFS cases — should not expect PT-141 (bremelanotide) or melanotan to restore function. He argues these peptides cannot overcome the underlying biological damage caused by finasteride because the root biology has been permanently altered.
Semax and PT-141 mentioned as ineffective against SSRI-induced sexual dysfunction
In discussing SSRI side effects (60% sexual dysfunction rate), the speaker briefly mentions that 'you can take all the Semax and PT-141 you want' — implying these peptides cannot overcome SSRI-induced sexual dysfunction because the root cause is systemic serotonin dysregulation affecting the entire neuroendocrine system, not just localized sexual function.